Individuals with Cornelia de Lange syndrome may have dental abnormalities such as missing teeth, small teeth, or misaligned teeth. They may also have a high arched palate, which can cause speech difficulties. It's important for individuals with CDLS to have regular dental checkups and work with a dentist who is familiar with the condition. In addition to dental abnormalities, individuals with Cornelia de Lange syndrome may have a range of physical, cognitive, and behavioral challenges. Some of the physical features of CDLS include small stature, limb abnormalities, and distinctive facial features. Cognitive challenges may include intellectual disability, learning difficulties, and speech delays. Behavioral challenges may include self-injurious behavior, anxiety, and hyperactivity. CDLS is a complex condition, and treatment often involves a team of specialists working together to address the individual's unique needs.